Acivir IV Injection | Acyclovir | For Herpes Zoster Infections

Introduction of Acivir IV Injection

Acivir IV Injection is a powerful antiviral medication used for the treatment of severe herpesvirus infections. It contains Acyclovir, a synthetic nucleoside analogue with strong activity against Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), and Cytomegalovirus (CMV) in certain cases. This intravenous formulation is designed for hospital use in patients who require rapid and effective antiviral treatment due to the seriousness of their condition or inability to take oral medications.

✅ How It Works:

Acyclovir works by inhibiting the replication of viral DNA. Once inside virus-infected cells, it gets converted into its active triphosphate form, which selectively inhibits viral DNA polymerase, thereby halting virus multiplication without damaging healthy human cells.

✅ Key Benefits of Acivir IV Injection:

• Rapid and reliable antiviral action in life-threatening herpes infections
  
  

• Essential in immunocompromised patients unable to mount an effective immune response
  
  

• Ideal for patients who cannot take oral antiviral medications
  
  

• May reduce complications and mortality in severe HSV and VZV infections
  
  
  

✅ Precautions & Warnings:

• Use with caution in patients with renal impairment – dosage adjustments required
  
  

• Monitor for signs of neurotoxicity (e.g., tremors, confusion, hallucinations)
  
  

• Ensure adequate hydration during treatment to reduce kidney risks
  
  

• Should only be used under the direction of a medical professional
  
  

✅ Possible Side Effects:

Common Side Effects:

• Nausea
  
  

• Vomiting
  
  

• Local irritation at injection site
  
  

• Headache
  
  

Serious Side Effects (rare):

• Renal toxicity
  
  

• Neurotoxicity (e.g., confusion, agitation, seizures)
  
  

• Hypotension
  
  

• Allergic reactions
  
  

✅ Storage Instructions:

• Store below 25°C, protected from light
  
  

• Use under sterile, aseptic conditions only
  
  

• Keep out of reach of children
  
  

Acivir IV Injection plays a crucial role in managing severe, potentially life-threatening viral infections. It is particularly important for hospitalized and immunocompromised patients, delivering fast-acting antiviral protection when oral medications are insufficient or inappropriate.